We have not talked much about the flu on UsefulChem but this article might be of interest since there is a real target to think about. A next step would be to obtain the pdb file and start to look at docking. From Chemistry World:
Structure of key influenza A protein revealed
06 December 2006
The crystal structure of a molecule important for the replication of the influenza A virus has been solved, report US researchers. Now that scientists know what the protein looks like they can design drugs that block its action and prevent viral spread through the body.