I just saw a post on the SynapticLeap by Anatoly Chernyshev about a docking program that sounds perfect for our needs:
If you need a quick assessment of the docking mode for a molecule, the best tool IMHO is ArgusLab (http://www.arguslab.com). It's free, runs under Win and has very good user interface. The tutorial is also supplied, so that average person can learn the software in one evening. It can dock molecular libraries without user intervention. I also found its performance comparable to more advanced packages (Dock, AutoDock). Perhaps, it will not show all 'best hits', but it, definitely, discards the wrong ones.Lets find out how good it is. Anybody out there have experience with ArgusLab?