carborane binds to HIV protease
From Science Blog
"The metallacarboranes appeared to occupy the portion of the protease used to hold key proteins in place as part of the infective cycle of HIV, preventing the proteases from working."
They used X-Ray Crystallography to show the binding site.
Relevant to:
anti-HIV compounds
HIV protease inhibitors
1 Comments:
Ted - thanks for the note. Feel free to share any insights you might have on the projects here.
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